Donat Kögel Selected Research

Sirolimus (Rapamycin)

11/2021

Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death.

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Donat Kögel Research Topics

Disease

30	Neoplasms (Cancer) 01/2022 - 07/2008
27	Glioma (Gliomas) 11/2021 - 02/2008
15	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 09/2010
6	Hypoxia (Hypoxemia) 04/2016 - 10/2002
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 02/2002
4	Alzheimer Disease (Alzheimer's Disease) 01/2017 - 05/2009
3	Breast Neoplasms (Breast Cancer) 01/2018 - 02/2003
3	Neuroblastoma 09/2012 - 08/2003
2	Starvation 01/2021 - 04/2016
2	Brain Neoplasms (Brain Tumor) 09/2020 - 01/2015
2	Urinary Bladder Neoplasms (Bladder Cancer) 02/2016 - 04/2015
2	Astrocytoma (Pilocytic Astrocytoma) 01/2014 - 08/2008
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2009 - 07/2008
2	Ischemia 05/2008 - 08/2003
1	Edema (Dropsy) 01/2021
1	Colonic Neoplasms (Colon Cancer) 01/2021
1	Triple Negative Breast Neoplasms 01/2018
1	Testicular Neoplasms (Testicular Cancer) 03/2016
1	Leukemia 07/2015

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2003
7	Pharmaceutical PreparationsIBA 01/2022 - 07/2008
6	GossypolIBA 03/2019 - 07/2010
6	Transcription Factors (Transcription Factor)IBA 01/2017 - 02/2002
5	ABT-737IBA 01/2017 - 07/2010
4	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2022 - 07/2013
4	Cytochromes c (Cytochrome c)IBA 07/2015 - 02/2003
3	Loperamide (Imodium)FDA LinkGeneric 11/2021 - 01/2018
3	Phosphotransferases (Kinase)IBA 11/2021 - 01/2013
3	Amyloid (Amyloid Fibrils)IBA 01/2017 - 05/2009
3	CaspasesIBA 01/2017 - 08/2002
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 11/2021 - 01/2021
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2021 - 01/2021
2	Cathepsin BIBA 11/2021 - 01/2014
2	Pimozide (Orap)FDA Link 11/2021 - 01/2018
2	Temozolomide (Temodar)FDA LinkGeneric 07/2021 - 01/2014
2	EnzymesIBA 07/2021 - 01/2013
2	bafilomycin A1IBA 01/2021 - 01/2014
2	Amino Acids FDA Link 01/2021 - 04/2016
2	GANT 61IBA 11/2019 - 03/2019
2	Antineoplastic Agents (Antineoplastics)IBA 03/2019 - 01/2014
2	Small Interfering RNA (siRNA)IBA 03/2019 - 01/2018
2	gossypol acetic acidIBA 01/2018 - 01/2017
2	Peptides (Polypeptides)IBA 01/2017 - 05/2009
2	Beclin-1IBA 04/2016 - 05/2008
2	Glucose (Dextrose)FDA LinkGeneric 04/2016 - 02/2002
2	Therapeutic UsesIBA 04/2015 - 12/2010
2	Thromboplastin (Tissue Factor)IBA 10/2013 - 10/2010
2	Biological ProductsIBA 02/2011 - 05/2008
2	CurcuminIBA 12/2010 - 09/2010
2	ethyl 2- amino- 6- bromo- 4- (1- cyano- 2- ethoxy- 2- oxoethyl)- 4H- chromene- 3- carboxylateIBA 07/2010 - 08/2008
2	Death Domain ReceptorsIBA 07/2008 - 04/2008
2	AntibodiesIBA 04/2008 - 02/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2006 - 10/2002
2	CeramidesIBA 08/2002 - 02/2002
1	Oncogene Proteins (Oncogene Protein)IBA 01/2022
1	NADPH Oxidase 2IBA 11/2021
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 11/2021
1	Sirolimus (Rapamycin)FDA Link 11/2021
1	Ribosomal Protein S6IBA 11/2021
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 11/2021
1	Bovine Serum AlbuminIBA 11/2021
1	Serotonin ReceptorsIBA 11/2021
1	dihydroceramide desaturaseIBA 11/2021
1	Lysosomal-Associated Membrane Protein 1IBA 11/2021
1	Valosin Containing ProteinIBA 11/2021
1	Vitamin D3 24-HydroxylaseIBA 07/2021
1	Cholecalciferol (Vitamin D3)FDA Link 07/2021
1	Calcitriol (Calcijex)FDA LinkGeneric 07/2021
1	VitaminsIBA 07/2021
1	gamma-Aminobutyric Acid (GABA)IBA 01/2021
1	Activating Transcription Factor 6IBA 01/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2021
1	Peptide Initiation Factors (Initiation Factor)IBA 01/2021
1	DiarylheptanoidsIBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	Prokaryotic Initiation Factor-2IBA 01/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021
1	PiperidonesIBA 01/2021
1	A-1210477IBA 11/2019
1	Arsenic Trioxide (Trisenox)FDA Link 03/2019
1	PolyethyleneimineIBA 03/2019
1	Phospholipids (Phosphatides)FDA LinkGeneric 03/2019
1	colfosceril palmitate FDA Link 03/2019
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2018
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2018
1	Mitochondrial Permeability Transition PoreIBA 01/2018
1	Heme Oxygenase-1IBA 01/2018
1	STF 62247IBA 01/2018
1	N-(3-pyridylmethyl)adriamycin (YM 1)IBA 01/2017
1	Topotecan (Hycamtin)FDA LinkGeneric 01/2017
1	N2- (1H- indazole- 5- yl)- N6- methyl- 3- nitropyridine- 2,6- diamineIBA 01/2017
1	DEVDaseIBA 07/2015
1	Sorafenib (BAY 43-9006)FDA Link 07/2015
1	Gemcitabine FDA Link 04/2015

Therapy/Procedure

21	Therapeutics 01/2022 - 02/2008
5	Drug Therapy (Chemotherapy) 09/2020 - 06/2011
2	Transplantation 07/2021 - 03/2019
2	Aftercare (After-Treatment) 04/2015 - 02/2011
1	Radiotherapy 09/2020
1	Chemoradiotherapy 03/2019